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Dr. Andrew M. Khoury and Amanda Worsham, FNP-C, of Advanced Spine and Pain Specialists

Interventional pain management

Treat pain at its source. Get your life back.

Minimally invasive, board-certified pain care for the neck, back, joints and nerves, delivered with compassion in The Woodlands and Liberty, Texas.

Affiliated withMemorial HermannHouston Methodist
Houston Chronicle Best of the Best 2025Houston Chronicle Best of the Best 2024 Finalist

Voted by Houston

Houston Chronicle’s Best of the Best pain management clinic.

2025 winner · 2024 finalist

4.91437 patient reviewsRead reviews
Dr. Andrew M. Khoury, MD

His motto

“For without compassion, medicine is merely science.”

Meet the founder

Andrew M. Khoury, MD

Dr. Khoury is double board-certified, in anesthesiology by the American Board of Anesthesiology and in interventional pain management. He founded Advanced Spine and Pain Specialists in The Woodlands and Liberty, Texas, with one goal: find the true source of chronic pain and treat it with gentle, minimally invasive care.

He started his career as an emergency medical technician, and has published his own research and volunteered for years. His expertise includes kyphoplasty, spinal cord and DRG stimulation, peripheral nerve stimulation, pain pumps, indirect lumbar decompression for stenosis, and an in-office ketamine infusion protocol for hard-to-treat pain.

Member of

  • American Society of Pain and Neuroscience
  • American Society of Interventional Pain Physicians
  • Texas Pain Society
  • Texas Medical Association

Our team

Specialists who listen first.

A board-certified physician and a nurse practitioner working together on one plan for your pain.

  • Andrew M. Khoury, MD

    Andrew M. Khoury, MD

    Founder · Double board-certified pain specialist

    Dr. Khoury founded Advanced Spine and Pain Specialists to treat chronic pain at its source. He has extensive experience with minimally invasive techniques including kyphoplasty, spinal cord and DRG stimulation, peripheral nerve stimulation, intrathecal pump therapy and indirect lumbar decompression, and runs an in-office ketamine infusion protocol for hard-to-treat pain.

    Read full profile
  • Amanda Worsham, MSN, APRN, FNP-C

    Amanda Worsham, MSN, APRN, FNP-C

    Family nurse practitioner

    Amanda has practiced in pain management since earning her nurse practitioner license from the University of Texas at Tyler. She is passionate about patient education and long-term relationships with patients. Her favorite therapies include spinal cord stimulation, ReActiv8 and the intrathecal pain pump.

    Read full profile

Boards, awards & education

From biomedical engineering to a multidisciplinary pain fellowship, each step built on the last.

  1. 01/Undergraduate

    B.S. Biomedical Engineering, University of Houston

  2. 02/Medical School

    University of Texas Medical School at Houston

  3. 03/Internship

    General Surgery, Baylor College of Medicine

  4. 04/Residency

    Anesthesiology, University of Texas Medical Branch, Galveston

  5. 05/Fellowship

    Multidisciplinary Pain Medicine, University of Florida

Board certification

American Board of Anesthesiology

Interventional Pain Management

Dual board-certified: anesthesiology and interventional pain management.

Awards

Houston Chronicle Best of the Best 2025Houston Chronicle Best of the Best 2024 Finalist
  • Houston Chronicle Best of the Best2025
  • Best of the Best Finalist2024

Why choose us

Less pain, more life. That is the goal.

We find where your pain comes from, then treat it with the least invasive option that will work, so you can get back to work, family and the things you enjoy.

A provider comforting a patient
  • Board-certified expertise

    Dr. Khoury is board-certified in anesthesiology and interventional pain management, and fellowship-trained at the University of Florida.

  • Advanced, minimally invasive options

    From spinal cord and DRG stimulation to MILD®, kyphoplasty, Intracept® and ketamine infusions: treatments that target the source of pain.

  • Compassion first

    “For without compassion, medicine is merely science.” We listen, explain your options clearly and decide together.

A calm, modern clinic waiting room

Voted by Houston

Houston Chronicle’s Best of the Best, two years in a row.

Chronic pain affects 1 in 3 Americans, more than heart disease and cancer combined. We are honored that our patients trust us to help.

In proud affiliation withMemorial HermannHouston Methodist
  • 4.91/5

    Average rating, 437 reviews

  • 2x

    Best of the Best, 2024 and 2025

  • 2

    Locations: The Woodlands and Liberty, TX

Patient stories

In their words.

Rated 4.91 out of 5 from 437 patient reviews.

A smiling, happy patient
I have had back injections for years with no success. Dr. Khoury did my injections on Friday and on Sunday I am 100% pain free for the first time in over 30 years!
Laira A.Injection patient

Get in touch

Tell us where it hurts. We’ll take it from there.

Request an appointment at our The Woodlands or Liberty office and our team will call you back.

Request an appointment

Please don’t include medical records here. We’ll ask for them securely once we’ve spoken.

Dr. Khoury and Amanda Worsham, FNP-C